What is PIMS?
Paediatric Multisystem Inflammatory Syndrome (called PIMS-TS or PIMS for short) is rare. It occurs in less than 0.5% of children who have had COVID-19. Most children will not be seriously affected but in a very small number of cases it can be serious.
Children with PIMS have serious inflammation throughout their body. Inflammation is a normal response of the body’s immune system to fight infection. But sometimes the immune system can go into overdrive and begin to attack the whole body and if this happens, it is important that children receive urgent medical attention.
Doctors are concerned that in severe cases of PIMS the inflammation can spread to blood vessels (vasculitis), particularly those around the heart. If untreated, the inflammation can cause tissue damage, organ failure or even death.
Some of the symptoms of PIMS can overlap with other rare conditions, such as Kawasaki disease and Toxic Shock Syndrome. Like PIMS, complications from Kawasaki can cause damage to the heart. Kawasaki tends to affect children under five whereas PIMS seems to affect older children and teenagers.
Can PIMS be treated?
Yes. Doctors know what to look out for and will do tests to diagnose what’s wrong and what treatment to give your child. Even where doctors aren’t 100% sure whether a child or teenager has PIMS, they know how to treat the symptoms associated with it. Doctors use the same type of treatments to ‘reset’ the immune system for both PIMS and Kawasaki disease.
Researchers hope to find out more about how to diagnose children as quickly as possible and which are the most suitable treatments for each child.
What symptoms should I look out for?
All children with PIMS will have a temperature which continues over several days. There is a wide range of other symptoms children may have including tummy pain, diarrhoea, vomiting, rash, cold hands and feet or red eyes. These can be found in other illnesses too.
While most won’t be seriously unwell, some children may be severely affected by the syndrome. The most important thing is to remember that any child who is seriously unwell needs to be treated quickly – whatever the illness. The advice to parents remains the same: COVID-19 is extremely unlikely to make your child unwell; if you are worried about your child, take a look at the red/amber/green symptom guide above and if required, contact NHS 111 or your GP for urgent advice, or 999 in an emergency. If a professional tells you to go to hospital, please go to hospital.
If your child doesn’t have these signs of being seriously unwell but you are still concerned, call NHS 111 or contact your GP.
How many children have been affected?
It’s difficult to say because doctors are still in the process of reporting back and also because there isn’t a definitive test. However between April and June 2020 doctors reported seeing around 200 children with the condition.
Doctors are continuing to collect information about the ways that PIMS affects children.
Have any children died from PIMS?
We don’t know for sure because there isn’t a test for this condition. Doctors think two children may have died but they can’t be certain that there weren’t other reasons why these children died. These deaths are very sad indeed but doctors believe deaths in children related to PIMS are very, very rare. Many more children die of other infections such as flu or even chicken pox every year.
Is PIMS caused by COVID-19?
PIMS seems to be linked to COVID-19 because most of the children either had the virus or tested positive for antibodies showing they had been infected (even if they hadn’t seemed ill at the time). But a very small number of the children with PIMS symptoms didn’t test positive.
How can doctors tell if a child has PIMS?
There currently isn’t a test which will say whether a child definitely has the syndrome. A syndrome is a collection of many different symptoms which, together, can give doctors an indication of whether or not someone has a particular illness. Doctors will look for a pattern of symptoms relating to PIMS and then do more tests, such as blood pressure and blood tests, to make a diagnosis.
Are black or Asian children more likely to be affected?
Children from all ethnic minority backgrounds have been affected by PIMS. There have been more children affected by PIMS who are from Black and Asian backgrounds, but it is not clear what the reasons for this are at the current time. It is possible that this is because there were higher numbers of COVID-19 cases in these communities. But it is important for families with all ethnic backgrounds to be aware of the signs and symptoms of the condition, however rare.
There is more information available from the Royal College of Paediatrics and Child Health.